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Office of Health Economics | OHE

The Bulletin

Your biweekly update on health economics, policy, and impact

See how disease severity shapes priorities, watch key health policy insights from 2025 and our predictions in 2026, and see why investing in ALS treatments is timely and strategic.

  • Understanding Societal Preferences for Priority by Disease Severity in England and Wales

  • Watch on demand: 2025 Wrapped: Health, policy shifts & what’s next
  • ALS is at a turning point – and investing in treatments makes strategic sense

In a rush? That's your Bulletin summary done, or find the full story below.

Lotte Steuten | Deputy Chief Executive

Lotte Steuten, Deputy Chief Executive

The world is changing – can health systems keep up?

This week, the WHO announced that the UK has lost its status as a measles-free country after a rise in deaths from the disease and decline in childhood MMR vaccination rates.  

 

The global decline in immunisation rates is a growing public health challenge, and is set to be one of the shifts defining health policy in 2026. Addressing the root causes of this decline, including lack of accessibility and vaccine hesitancy, must be a core priority for health systems going forward, especially in light of an expanding portfolio of life course vaccinations and the strong evidence around their health and societal value.  

 

This then raises the question of how health systems should evolve to keep pace with a rapidly changing world. Part of this lies in how societal preferences are considered in health technology assessments (HTA). Our most recently published peer-review paper sought to understand how NICE’s severity modifier aligned with public preferences, concluding that if NICE seeks to reflect societal preferences in its assessments, it may need to revise the parameters of its modifier.   

 

New peer-reviewed journal on how well NICE’s severity modifier reflect public values 

Understanding Societal Preferences for Priority by Disease Severity in England and Wales

 

A new peer-reviewed Value in Health study finds that the public places greater value on health gains for patients with more severe disease, starting at much lower levels of health shortfall than NICE’s current thresholds. If NICE aims to better reflect societal preferences, the parameters of the severity modifier may need to be reconsidered.

Public perspectives on health gains and disease severity

2025 Wrapped: Health, policy shifts & what’s next

In January we recapped the biggest topics in health economics from 2025 across policy, prevention, and health technology assessments (HTA) and shared predictions and themes that will define the year ahead.

Catch up on the key takeaways

The commercial case for investing in ALS

ALS is at a turning point – and investing in treatments makes strategic sense

 

Amyotrophic lateral sclerosis (ALS) – the most common form of motor neurone disease – is a rare but devastating disease. It places a heavy toll on patients, families, and healthcare systems, yet progress in the development of new diagnostics and treatments has so far been limited.  

How a successful new treatment for ALS could be worth billions

Raising awareness of ALS: Crossword

 

See how much you know about ALS, its impact, and emerging treatments. For the full picture, check out our publication, The commercial case for investing in ALS, and learn more about the latest insights and opportunities in ALS research.

 

Test your knowledge on ALS with our quick crossword!

If you’ve made it to the end and enjoyed this edition, hit reply and share one insight that stood out to you.

Office of Health Economics | OHE

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