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OHE Bulletin

Simon Brassel

Guest editor: Simon Brassel | Senior Principal Economist

Turning differences into progress

 

Differences are a funny thing. We often see them as obstacles and reasons for conflict, but they are also drivers of progress. Just as differences in potential drive an electric current, differences in viewpoints can facilitate knowledge exchange and constructive debate. Three of OHE’s highlights this month deal with differences, one way or another.

 

Our latest research publication explores the difference 

between the potential value-based prices of future gene therapies and public budget holders’ ability to pay. Budget impact analysis (BIA) plays a role in informing related healthcare decision-making, but does it adequately capture the trade-offs between short term affordability and long-term benefits from such therapies? Our team reviews the approaches to and applications of BIA for gene therapies across various European countries and provides recommendations for its future use.

 

At OHE, we are also co-leading a project that acknowledges the value of different viewpoints and an interdisciplinary approach to research. Together with the London School of Hygiene and Tropical Medicine (GHECO and CCPH) and the Euro-Mediterranean Centre on Climate Change (CMCC), our Wellcome Trust-funded consortium aims to bridge the gap between how economic evaluation and environmental economics value the health co-benefits of adaptation and mitigation strategies, and to develop globally consistent and accessible guidance on the economic evaluation of the health impacts of climate action.

 

Our upcoming event “Investing in Innovation: A Spotlight on Haemophilia Therapies” will highlight a difference that is fundamental to OHE’s raison d'être: how do we ensure that future health innovations reconcile the difference between unmet health needs and what is actually possible? This webinar will be useful for a wide range of stakeholders that are interested in health technology assessment, including (but not limited to) payers, patient advocacy groups, regulators, health data scientists, academics, and industry.

 

Admittedly current changes in international cooperation in the US, and their impact on global health policy and outcomes make it seem that some differences are too hard to reconcile. Now, more than ever, it is important that OHE and others continue their efforts to turn differences into progress.

Our latest publication on Budget Impact Analysis

Challenges and Solutions for Budget Impact Analysis of Gene Therapies

Challenges and Solutions for Budget Impact Analysis of Gene Therapies

 

Gene therapies hold the potential to transform lives, but their high upfront costs present challenges for budget impact analysis (BIA). Can current BIA methods fully capture the long-term value of these treatments? A new publication highlights how more flexible approaches could help balance affordability and innovation.

Read the key takeaways

Fresh insight on OHE's contribution to EuroQol

EQ-5D and beyond: OHE’s contributions to EuroQol research and meetings

EQ-5D and beyond: OHE’s contributions to EuroQol research and meetings

 

How do we quantify the value of health? The EQ-5D plays a central role in health economic evaluations, with recent discussions highlighting key challenges in its application. The latest findings from the UK&I EQ-5D Researchers Meetingoffering insights on the potential impact of EuroQol’s Bolt-on Toolbox on health outcome measurement.

Learn more
Eco-Chica

 We want to hear from you!

 

The ECO-CHICA project — funded by the Wellcome Trust and led by OHE, LSHTM, and CMCC — is inviting expertise from health and environmental economics to develop practical, globally consistent guidelines for economic evaluation.

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EVIA Programme

EVIA Programme

This programme builds the capacity and confidence of sub–Saharan African policymakers and immunisation managers, and provides a foundational understanding of evidence–based decision–making on vaccination programmes.

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