As overburdened healthcare systems continue to see mounting demand, the question of trade-offs and resource allocation becomes all the more pressing. Underpinning that is the increasing role of health economics in determining priority setting in healthcare.
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October 2024

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Guest editor: Chris Skedgel | Director

As often overburdened healthcare systems continue to see mounting demand, the question of how to make efficient – and fair! – allocations and trade-offs between different diseases becomes all the more pressing. This emphasises the increasing role for health economics in informing priority-setting in healthcare.  

 

Understanding the preferences of those most affected by healthcare policies is central to efficient and fair decision making. As our recent publication found, incorporating patient voices in health technology assessments can help reassure patients and the public that HTA deliberations are being made on bases that they can trust, and can signal to industry stakeholders what health systems are willing to pay

for. Explicitly accounting for patient preferences can therefore have wide-ranging benefits for patients, health systems,  industry, and wider society.   

 

Having a coherent understanding of the needs of both patients and health systems can also improve innovation by allowing industry to recognise and respond to areas of unmet need. Our latest report looks at how Target Product Profile specifications (TPP) can provide innovators with a clear demand signal about the types of tests needed to improve the diagnostic landscape in oncology. Dr. Amanda Cole, an Associate Director at OHE, was quoted in Cancer Research UK’s blog on the report, which outlines how to develop robust, fit-for-purpose diagnostic TPPs for cancer. 

 

The role of public preferences in HTA decision making was made clear in England recently, when the National Institute for Health and Care Excellence’s (NICE) decision not to recommend the breast cancer drug Enhertu for funding on the UK’s National Health Service led to controversy. This decision hinged, in large part, on how NICE defines “severe diseases”, and on how much priority severe diseases should receive relative to less-severe diseases in NICE’s deliberation process. OHE has argued that an understanding of societal preferences are crucial to appropriate severity categorisations. 

 

I will be participating in a panel on a similar question of fairness, around how (or whether) HTA should consider bereavement and grief following the death of a patient. This is just one of a number of OHE panels and presentations at ISPOR Europe later this month, along with sessions on how to account for climate change in HTA, the pricing and reimbursement of multi-indication medicines, and more.  

Must-read OHE Publication

Incorporating the Patient Voice in Health Technology Assessment

Incorporating the Patient Voice in Health Technology Assessment

 

Incorporating the patient perspective in health technology assessments (HTA) is critical for making fully informed decisions about healthcare technologies.

 

Engaging patients early in development and valuing their input equally with clinical and economic evidence can guide innovation toward technologies that resonate with healthcare systems and society.

 

How can we ensure the patient voice is effectively integrated into the HTA process?

Read more

Insights For You

Using Target Product Profiles (TPPs) to improve diagnostic testing for cancer

Using Target Product Profiles (TPPs) to improve diagnostic testing for cancer

 

Early cancer diagnosis and treatment enhance patient outcomes, and Target Product Profiles (TPPs) play an important role in achieving this goal.

 

By outlining the essential requirements for new diagnostic tests, TPPs help signal the needs of patients and health systems to innovators.

 

Our latest report analyses how TPPs can guide oncology diagnostic advancements, as highlighted in Cancer Research UK’s recent blog on developing effective diagnostic specifications.

Read more
NICE’s severity modifier: a step in the right direction, but still a long way to go

NICE’s severity modifier: a step in the right direction, but still a long way to go

 

The 2022 introduction of NICE’s severity modifier marks a shift in health technology assessments, using Absolute and Proportional QALY Shortfall measures to redefine disease severity.

 

This framework allows for a broader assessment of the quality-adjusted life years lost, with QALY weights applied in three categories to increase the cost-effectiveness threshold.

 

While other countries like the Netherlands and Norway use similar measures, does NICE’s unique approach align with public preferences?

Read more

2024 Innovation Policy Prize Award Ceremony

Innovation Policy Prize
Register now

OHE at ISPOR Europe 2024

iOHE at ISPOR Europe 2024

Meet OHE experts at ISPOR Europe this year from 17-20 November in Barcelona.

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