How are HTA methods evolving? Explore key trends from NICE and global research.
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OHE Bulletin

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Guest editor: Helen Hayes | Associate Principal Economist

Improving healthcare resource allocation through better evidence and measurement 

 

This week, it was reported that the US had plans to cut roughly a third of its federal healthcare budget. In the UK, GPs in Scotland are raising the alarm about a £290 million funding gap in NHS services. All this raises the important question of how – and how much – we pay for healthcare. OHE’s recent publications offer perspectives on how we should allocate healthcare resources more effectively through better evidence and measurement. 

 

Our most recent publication looks at global immunisation funding, and highlights that despite the societal and economic value of immunisation programmes, expenditure remains disproportionately low. The report calls for governments to reassess national immunisation spending, review approaches to increase and protect prevention funding, enhance programme delivery, and improve data collection and reporting. 

 

The growing recognition that healthcare interventions may perform differently in real-world settings compared to clinical trials has raised the importance of Real-World Evidence (RWE). RWE can be informative for decision-makers for determining cost-effectiveness and value in healthcare financing. One of our reports in this Bulletin focuses on best practices for the generation and use of RWE, and looks at key considerations for its use to assess clinical and comparative effectiveness to inform HTA reimbursement decisions.  
 

Alongside these broader approaches to evidence and funding, a recent blog discusses insights from new research to develop a “cognition bolt-on” for the EQ-5D-5L instrument. The research explores how best to measure cognition, which is increasingly recognised as central to health-related quality of life. By improving how we measure health outcomes, we can better inform resource allocation decisions, in particular where determining cost-effectiveness is challenging due to subtle health status changes.  

 

Immunisation spending: strategic investment or afterthought?

Analysing Global Immunisation Expenditure

Analysing Global Immunisation Expenditure

 

Are health systems undervaluing the long-term benefits of immunisation? Despite being one of the most cost-effective public health tools, funding for vaccines remains surprisingly low. A recent analysis across 10 countries uncovers significant gaps in investment, data, and delivery, particularly for adult vaccination programmes.

Read the policy insight

Is a cognition bolt-on the missing link for EQ-5D?

Adding a “Cognition Bolt-on” to EQ-5D-5L: Insights from New Research and What’s Next

Adding a “Cognition Bolt-on” to
EQ-5D-5L

 

Cognition is under the spotlight as a potential EQ-5D-5L bolt-on. The EuroQol-funded study is testing whether memory and concentration offer more value than a single broad item. Early findings highlight implications for HTA, dementia research, and measuring outcomes in recovery and mental health. Could a more targeted approach to cognition improve how we capture health-related quality of life?

Review early findings

Improving patient access with better evidence

Real-World Evidence: Current Best Practice for Reimbursement Decision-Making

Current Best Practice for Reimbursement Decision-Making

 

Real-world evidence (RWE) can offer valuable insights for patient access decisions, but it’s still underused in reimbursement processes. This report highlights best practices for generating and using RWE, based on guidelines from top Health Technology Assessment bodies. 

Read more

As an employer, have you considered the impact of respiratory infections on productivity? 

 

A new interactive Respiratory Cost Calculator, developed by OHE, commissioned and owned by Pfizer, enables employers to estimate the financial impact of absenteeism and presenteeism due to short-term respiratory illnesses.

 

Job code: PP-UNP-GBR-12111 April 2025

Calculate now
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